Publication:


abstract

AIM:

The aim of this study was to assess the miscarriage and fetal loss rates of twin pregnancies after amniocentesis.

MATERIAL AND METHODS:

The Outcome of 140 twin pregnancies that had amniocentesis performed from 1997 to 2006 was reviewed.

RESULTS:

Among 140 twin pregnancies with amniocentesis, 35 were excluded (fetuses with structural anomalies, post-selective feticide, abnormal fetal karyotype, twin-twin transfusion syndrome [TTTS], termination of pregnancy, and unknown outcome). For the remaining 105 twin pregnancies, 102 had live births of all fetuses. One dichorionic twin had silent miscarriage of one fetus at 23 weeks. Another dichorionic twin had intrauterine death of one fetus at unknown gestation. One patient had preterm delivery at 32 weeks with neonatal death of one twin due to severe intrauterine growth restriction. The miscarriage rate (one or both fetuses) for twins before 24 weeks was 0.96% (1/105), the pregnancy loss (one or both fetuses) within 4 weeks of amniocentesis was 0.96% (1/105). The total fetal loss rate was 0.96% (2/210) for twins.

CONCLUSION:

Our cohort showed a low fetal loss rate after amniocentesis for uncomplicated twin pregnancies.

© 2012 The Authors. Journal of Obstetrics and Gynaecology Research © 2012 Japan Society of Obstetrics and Gynecology.

Related Articles
Review Dilemmas in the management of twins discordant for anencephaly diagnosed at 11 + 0 to 13 + 6 weeks of gestation.
Ultrasound Obstet Gynecol. 2006
Review Dilemmas in the management of twins discordant for anencephaly diagnosed at 11 + 0 to 13 + 6 weeks of gestation.
Vandecruys H, Avgidou K, Surerus E, Flack N, Nicolaides KH. Ultrasound Obstet Gynecol. 2006 Oct; 28(5):653-8.
Ductus venosus Doppler at 11 to 13 weeks of gestation in the prediction of outcome in twin pregnancies.
Obstet Gynecol. 2009
Ductus venosus Doppler at 11 to 13 weeks of gestation in the prediction of outcome in twin pregnancies.
Maiz N, Staboulidou I, Leal AM, Minekawa R, Nicolaides KH. Obstet Gynecol. 2009 Apr; 113(4):860-5.
Risk of fetal loss in twin pregnancies undergoing second trimester amniocentesis(1).
Obstet Gynecol. 2001
Risk of fetal loss in twin pregnancies undergoing second trimester amniocentesis(1).
Yukobowich E, Anteby EY, Cohen SM, Lavy Y, Granat M, Yagel S. Obstet Gynecol. 2001 Aug; 98(2):231-4.
Fetal death in twins.
Acta Obstet Gynecol Scand. 2011
Fetal death in twins.
Mahony R, Mulcahy C, McAuliffe F, Herlihy CO, Carroll S, Foley ME. Acta Obstet Gynecol Scand. 2011 Nov; 90(11):1274-80. Epub 2011 Aug 29.
Review Cord entanglement and perinatal outcome in monoamniotic twin pregnancies.
Ultrasound Obstet Gynecol. 2010
Review Cord entanglement and perinatal outcome in monoamniotic twin pregnancies.
Dias T, Mahsud-Dornan S, Bhide A, Papageorghiou AT, Thilaganathan B. Ultrasound Obstet Gynecol. 2010 Feb; 35(2):201-4.