Publication:


abstract

PURPOSE:

the authors compared the immediate, mid-term and long-term effectiveness of cryoplasty and conventional angioplasty for treating stenotic-occlusive lesions of the femoropopliteal arteries in diabetic patients.

MATERIALS AND METHODS:

From October 2006 to November 2009, 48 patients with non-insulin-dependent diabetes mellitus (DM) and an indication for percutaneous revascularisation of the femoropopliteal arteries were randomly assigned to treatment with angioplasty or cryoplasty. The following parameters were analysed and compared between the two groups: immediate technical success (residual stenosis <30%) and distal run-off as assessed on postprocedural angiography, and degree of restenosis and distal run-off at 6 and 12 months, as assessed with either colour Doppler ultrasound (CDUS) or digital subtraction angiography (DSA).

results:

Treatment with angioplasty revealed a significant superiority in procedural technical success (p=0.04), a significant reduction in the degree of restenosis at 6 months (p=0.02) and a significant increase in the distal run-off at 6 (p=0.005) and 12 (p=0.01) months.

CONCLUSIONS:

Conventional angioplasty is more effective than cryoplasty for treating stenotic-occlusive lesions of the femoropopliteal arteries in diabetic patients and provides better immediate, mid-term and long-term results.

Related Articles
Cryoplasty versus conventional balloon angioplasty of the femoropopliteal artery in diabetic patients: long-term results from a prospective randomized single-center controlled trial.
Cardiovasc Intervent Radiol. 2...
Cryoplasty versus conventional balloon angioplasty of the femoropopliteal artery in diabetic patients: long-term results from a prospective randomized single-center controlled trial.
Spiliopoulos S, Katsanos K, Karnabatidis D, Diamantopoulos A, Kagadis GC, Christeas N, Siablis D. Cardiovasc Intervent Radiol. 2010 Oct; 33(5):929-38. Epub 2010 Jun 24.
Infrapopliteal run-off and the outcome of femoropopliteal percutaneous transluminal angioplasty.
Vasa. 2010
Infrapopliteal run-off and the outcome of femoropopliteal percutaneous transluminal angioplasty.
Salapura V, Blinc A, Kozak M, Jezovnik MK, Pohar Perme M, Berden P, Kuhelj D, Kljucevsek T, Popovic P, Stankovic M, et al. Vasa. 2010 May; 39(2):159-68.
Cryoplasty for the treatment of femoropopliteal arterial disease: results of a prospective, multicenter registry.
J Vasc Interv Radiol. 2005
Cryoplasty for the treatment of femoropopliteal arterial disease: results of a prospective, multicenter registry.
Laird J, Jaff MR, Biamino G, McNamara T, Scheinert D, Zetterlund P, Moen E, Joye JD. J Vasc Interv Radiol. 2005 Aug; 16(8):1067-73.
Review Cryoplasty for the prevention of arterial restenosis.
Cardiovasc Intervent Radiol. 2...
Review Cryoplasty for the prevention of arterial restenosis.
Wildgruber MG, Berger HJ. Cardiovasc Intervent Radiol. 2008 Nov-Dec; 31(6):1050-8. Epub 2008 Jun 6.
Review Indications and results with cryoplasty in the treatment of infrainguinal arterial occlusive disease.
Vascular. 2006
Review Indications and results with cryoplasty in the treatment of infrainguinal arterial occlusive disease.
Lyden SP. Vascular. 2006 Sep-Oct; 14(5):290-6.